Genomics

Essay specific features

 

Issue:

Science

 

Written by:

Jorge P

 

Date added:

July 22, 2011

 

Level:

University

 

Grade:

B

 

No of pages / words:

5 / 1185

 

Was viewed:

7199 times

 

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Essay content:

The flow karyotyping method allows quantification of chromosomal DNA by flow cytometry and thus analysis of chromosomal aberrations on chromosome suspensions. Amounts of data providing statistical significance can be collected quickly and the approach allows accurate mapping of chromosomal DNA composition...
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The limitation of the method is at the cellular level of analysis, which is an impossibility to detect low-frequency or heterogeneous events, with this method. The aim of this intracellular flow karyotyping project is improving the technology to extend the method to the analysis of karyotype aberrations from individual cells...
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