DNA

Essay specific features

 

Issue:

Science

 

Written by:

Jacob M

 

Date added:

October 29, 2014

 

Level:

University

 

Grade:

B

 

No of pages / words:

4 / 1101

 

Was viewed:

3776 times

 

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Essay content:

Scientists recognized that this could potentially be a very powerful tool, and so there was competition to create a method that would sequence DNA. Then in 1974, two methods were independently developed by an American team and an English team to do exactly this. The Americans, lead by Maxam and Gilbert, used a “chemical cleavage protocol”, while the English, lead by Sanger, designed a procedure similar to the natural process of DNA replication...
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Even though both teams shared the 1980 Nobel Prize, Sanger’s method became the standard because of its practicality (Speed, 1992). Sanger’s method, which is also referred to as dideoxy sequencing or chain termination, is based on the use of dideoxynucleotides (ddNTP’s) in addition to the normal nucleotides (NTP’s) found in DNA...
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