hormone use in breast cancer

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Issue:

Science

 

Written by:

Terry V

 

Date added:

September 27, 2010

 

Level:

 

Grade:

A

 

No of pages / words:

16 / 4353

 

Was viewed:

546 times

 

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Essay content:

It has been used in breast cancer prevention, adjuvant treatment, prevention of contralateral breast cancers, and the treatment of metastatic breast cancer (MBC) (1, 2). Tamoxifen has been shown to decrease recurrence and mortality rates, but may be associated with serious side effects. These side effects include increased risk of endometrial cancer (3) and blood clotting (4, 5)...
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Although these side effects are rare, clinicians must be aware of these potential risks, and patient education of the risk:benefit ratio of tamoxifen, balancing potential toxicities with proven benefits, is required. Because of the potential side effects of tamoxifen, other hormonal therapies have been developed in an attempt to improve efficacy and safety...
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