How animal research has advanced the understanding of depression

Essay specific features

 

Issue:

Psychology

 

Written by:

Douglas E

 

Date added:

May 29, 2014

 

Level:

University

 

Grade:

A

 

No of pages / words:

8 / 2184

 

Was viewed:

6103 times

 

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Essay content:

The following stimuli were used as stressors which include: Continuous light for 2 12 hour periods Forty degree tilt along vertical axis of cage for 6 hour period Paired housing for a 16 hour period and 4 hour period Damp bedding with 300 mL water spilled on bedding for 16 hour period Water deprivation for 16 hour period Empty water bottle following 16 hour water deprivation for 1 hour Stroboscopic light with 300 flashes a minute for a 6 hour period and 4 hour period White noise at approximately 90 dB for 4 hour period of continuous noise and a 3 hour period with random intermittent noise All the stressors were given over a period of one week, and randomly presented for 3 additional weeks for a total of 4 week trial...
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All the rats were injected with a receptor agonist and were decapitated 15 minutes after the injection for the trunk blood. The 4 week trial resulted in the rats showing signs of depression, and satisfied adrenocorticotropic hormone (ACTH) responses to the receptor agonist. The trials also sparked a lack of pleasure in both male and female rats...
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