The Cystic Fibrosis Gene

Essay specific features

 

Issue:

Miscellaneous

 

Written by:

Sherry P

 

Date added:

July 22, 2014

 

Level:

University

 

Grade:

A

 

No of pages / words:

8 / 2168

 

Was viewed:

4114 times

 

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Essay content:

In this paper, I will be focusing on how the cystic fibrosis gene was discovered while at the same time, discussing the protein defect in the CF gene, the bio-chemical defect associated with CF, and possible treatments of the disease. Finding the Cystic Fibrosis Gene The classical genetic approach to finding the gene that is responsible for causing a genetic disease has been to first characterize the bio-chemical defect within the gene, then to identify the mutated protein in the gene of interest, and finally to locate the actual gene...
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However, this classical approach proved to be impractical when searching for the CF gene. To find the gene responsible for CF, the principle of "reverse genetics" was applied. Scientists accomplished this by linking the disease to a specific chromosome. After this linkage, they isolated the gene of interest on the chromosome and then tested its product...
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