Essay heading: A Cure Can Cause More Problems

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Science

 

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January 3, 1999

 

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6 / 1659

 

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These side effects are both a nuisance and dangerous. Isotretinoin is a synthetic form of vitamin A. As attested by Dr. Michael Miller, "High doses of vitamin A can cause headache, depression, fatigue, irritability, aggression, even personality change and psychosis -- a syndrome called hypervitaminosis...
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A part of the brain known as the orbitolfrontal cortex, which is presumed to control symptoms of depression, has shown a decrease in brain metabolism as a result of Isotretinoin ("Brain Imaging" 1). An article in the Brown University Child and Adolescent Psychopharmacology Update says, "The association is still controversial, however, because up to 5...
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