Achondroplasia is caused by a mutation in the FGFR3 gene. According to the NCBI, "nucleotide 1138 of the FGFR3 gene may be one of the most mutable bases in the human genome."
4. Achondroplasia is a dominant disorder... displayed 300 characters
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Achondroplasia is a dominant disorder. If two individuals with achondroplasia have children, what percentage of their children would be expected to be of normal height? What percentage would be expected to have the lethal homozygous dominant form? What percentage would be expected to have achondroplasia?
25% lethal homozygous dominant XiY
25% male achondroplasia
25% female achondroplasia XY
25% normal height
25% of their children are expected to be of normal height
25% of their children are expected to have the lethal homozygous dom... displayed next 300 characters
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The function of the normal gene product contains an extracellular region, composed of three immunoglobulin domains, a hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain (2)...
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