Only significant similarity between Interferon and Retrovir is that they both treat life-threatening diseases. Otherwise, they are not comparable in their market position, their development costs or their substitutes available. A reference product is a product that is the best alternative available to a consumer, its closest competitor, or a product that satisfies a similar need...
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Interferon does not meet any of these criteria. Interferon is a cancer treatment drug and hence is not an alternative for Retrovir, an AIDS drug. It does not compete with Retrovir and it satisfies completely different need in a completely different customer segment. Interferon is not the only treatment for cancer available to the patients...
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