These drugs affect the serotonin receptors, specifically the 5-HT2 receptors, and the effects of hallucinogens are caused by activity of serotonin containing neurons after synaptic transmissions occur in the brain. Also, there is evidence that certain psychedelics inhibit serotonin release of 5-HT1 serotonin transmitter receptors... displayed 300 characters
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These disruptions cause “hyperactivity of the frontal and occipital lobes, especially in the right hemisphere” when a brain on psilocybin is analyzed using PET scans (Lyvers, 2003). How these effects in the brain’s chemical transmissions cause psychedelic experience and hallucinations of sounds and sights that do not exist is still not understood... displayed next 300 characters
Also, they wanted to better understand LSD's effects on the serotonin receptor by comparing the potencies of various drugs on selective (H3)LSD binding compared to the high-affinity binding of (H3)serotonin...
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