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Essay

Risk of Cardiovascular Events with Rofecoxib

Essay specific features

 

Issue:

Science

 

Written by:

Jean M

 

Date added:

March 11, 2014

 

Level:

University

 

Grade:

A

 

No of pages / words:

5 / 1301

 

Was viewed:

5381 times

 

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Essay content:

This justifies the withdrawal of rofecoxib from the market. Introduction Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) which selectively inhibits the cyclooxygenase-2 (COX-2) enzyme.1 It was developed by Merck & Co. for the treatment of acute inflammation in joints, without causing the gastrointestinal side effects associated with traditional NSAIDs...
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2).4 Studies in mice and humans showed that COX-2 is the dominant source of prostaglandin I2, causing vasodilation as well as inhibiting platelet aggregation and vascular proliferation.4 The individual cardiovascular effects of prostaglandin I2 contrast with those of thromboxane A2 ? the major COX-1 product of platelets which cause platelet aggregation, vasoconstriction and vascular proliferation...
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General issues of this essay:
In looking for Alibrandi, several events occur during Josephine's final year at school. What are they and how do these events bring about change in Josephine? The characters and events of The Chronicles of Narnia: The Lion, the Witch and the Wardrobe have symbolic similarities to events described in the Bible. Factors Causing the Spanish Conquest Causing Generation X How John Donne Showed His Love Nuclear Proliferation The nuclear proliferation Totalitarian Society As Showed Changes In The Atmosphere Causing Multicellularity ISOTOPIC PALAEODIET STUDIES OF ANCIENT EGYPTIAN FAUNA AND HUMANS Risk Factors for Cardiovascular disease Risk of Cardiovascular Events with Rofecoxib Telomere Dysfunction and Evolution of Instestinal Carcinoma in Mice and Humans Nuclear Proliferation Open Source Software versus Closed Source Software
 

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