Hydrogen atoms press at ~129 MHz in a 3 T scanner ? Precession o Change in direction of the axis of a rotating object o RF (radio frequency)?pulse causes the orientation of the precessing nuclei to be rotated o A receiver coil near the head can detect the electromagnetic field generated by the precessing nuclei o Rate of signal decay following the RF (radio frequency) pulse differs from various tissues o This principle used to image local changes in blood flow ? +++BOLD response o Blood Oxygen Level Dependent response o As neuronal activity increases in the brain, there is a subsequent increase in blood flow o Leads to excess oxygenated blood o Shows up as an increase in the MR signal for that region o Increased neuronal activity ?increased local blood flow
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Hydrogen atoms press at ~129 MHz in a 3 T scanner ? Precession o Change in direction of the axis of a rotating object o RF (radio frequency)?pulse causes the orientation of the precessing nuclei to be rotated o A receiver coil near the head can detect the electromagnetic field generated by the precessing nuclei o Rate of signal decay following the RF (radio frequency) pulse differs from various tissues o This principle used to image local changes in blood flow ? +++BOLD response o Blood Oxygen Level Dependent response o As neuronal activity increases in the brain, there is a subsequent increase in blood flow o Leads to excess oxygenated blood o Shows up as an increase in the MR signal for that region o Increased neuronal activity ?increased local blood flow
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