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Drug Resistance Mechanisms In Cancer Cells

Essay specific features

 

Issue:

English

 

Written by:

Amber G

 

Date added:

September 14, 2011

 

Level:

University

 

Grade:

A

 

No of pages / words:

4 / 881

 

Was viewed:

1622 times

 

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Essay content:

Not much is known in regards to how MRP-1 confers multidrug resistance, a notable exception is that its expression has been associated with a decrease in drug accumulation similar to P-glycoprotein [1]. Glutathione is an important cellular antioxidant and detoxification protein, and its increased levels have been observed to inactivate various chemotherapeutic drugs [2]...
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Not much is known in regards to how MRP-1 confers multidrug resistance, a notable exception is that its expression has been associated with a decrease in drug accumulation similar to P-glycoprotein [1]. Glutathione is an important cellular antioxidant and detoxification protein, and its increased levels have been observed to inactivate various chemotherapeutic drugs [2]...
displayed 300 characters

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