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Issue:

Miscellaneous

 

Written by:

Loretta E

 

Date added:

April 17, 2015

 

Level:

University

 

Grade:

A

 

No of pages / words:

2 / 392

 

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2970 times

 

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DNA, however, is only synthesized during the S phase. DNA replication is started by Helicase which unwinds the double helix at replication forks. Topoisomerase is used to loosen the tension at the ends of the bubble, in order to correct for over winding ahead of the replication forks. Primase then synthesizes an RNA primer which the DNA polymerase III will use to lay down bases, synthesizing a new strand...
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Primase then synthesizes an RNA primer which the DNA polymerase III will use to lay down bases, synthesizing a new strand. DNA polymerase I will then remove the primer and DNA Ligase will join ends of DNA synthesized from different replication forks. Because DNA can only synthesize from 5'->3', there is a leading strand and lagging strand which creates Okazaki fragments that are later joined together by DNA Ligase...
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