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Essay

Hemophilia 3

Essay specific features

 

Issue:

Miscellaneous

 

Written by:

Ann P

 

Date added:

May 19, 2014

 

Level:

University

 

Grade:

A

 

No of pages / words:

3 / 620

 

Was viewed:

6467 times

 

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Essay content:

The level of severity of the disorder breeds true in any given family, which indicates that the phenotypic expression of the disorder reflects the genetic defect. In about 5% of cases, hemophilia-A results from partial deletion of the factor VIII gene, and is severe. Other cases result from a single base mutation in the gene...
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This can result in nonsense mutations which result in premature stop codons, and a severe expression of the disorder, or missense mutations which cause milder forms of the disorder. In some cases the disorder can also result from spontaneous mutations, but this is less common. The gene for hemophilia-A is located at Xq28 while the gene for hemophilia-B is located at Xq27...
displayed 300 characters

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