androgen blocking drugs and treating patients with mild heart failure

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Issue:

Science

 

Written by:

Samantha F

 

Date added:

March 7, 2015

 

Level:

University

 

Grade:

A

 

No of pages / words:

8 / 2026

 

Was viewed:

4046 times

 

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Essay content:

After a 3-week, open-label, up-titration period, 49 of the 56 patients were assigned (in a double-blind fashion using a 2:1 randomization) to receive either carvedilol (25 mg BID, n=33) or matching placebo (n=16) for 14 weeks, while background therapy remained constant. Hemodynamic and functional variables were measured at the start and end of the study...
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Hemodynamic and functional variables were measured at the start and end of the study. Compared with the placebo group, patients in the carvedilol group showed improved cardiac performance, as reflected by an increase in left ventricular ejection fraction (P=.005) and stroke volume index (P=.010) and a decrease in pulmonary wedge pressure, mean right atrial pressure, and systemic vascular resistance (P=...
displayed 300 characters

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