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Biology

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Issue:

Science

 

Written by:

Alecia R

 

Date added:

March 26, 2014

 

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Grade:

C

 

No of pages / words:

2 / 312

 

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5520 times

 

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This could be achieved by pre-computing the indexes of proteins and arranging them in a hash table. Then, queries are evaluated based on a voting scheme using the hash table. This voting scheme replaces the seed generation process. In this lecture, we look into the voting scheme used in 3dSEARCH [2]...
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The algorithm is based on the concept of geometric hashing [1] developed in the eld of computer vision. The basic idea is to represent all secondary structure elements (SSEs) from all target proteins with a large, highly redundant hash (or index) table. Once the table has been constructed, every SSE from a given query structure can be compared simultaneously to the entire set of SSEs of the target structures, by indexing the SSE into the table...
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