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DNA
Essay specific features
Written by:
Jacob M
Date added:
October 29, 2014
Level:
University
Grade:
B
No of pages / words:
4 / 1101
Was viewed:
4110 times
Rating of current essay:
Essay content:
Scientists recognized that this could potentially be a very powerful tool, and so there was competition to create a method that would sequence DNA. Then in 1974, two methods were independently developed by an American team and an English team to do exactly this. The Americans, lead by Maxam and Gilbert, used a “chemical cleavage protocol”, while the English, lead by Sanger, designed a procedure similar to the natural process of DNA replication...
displayed 300 characters
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Even though both teams shared the 1980 Nobel Prize, Sanger’s method became the standard because of its practicality (Speed, 1992).
Sanger’s method, which is also referred to as dideoxy sequencing or chain termination, is based on the use of dideoxynucleotides (ddNTP’s) in addition to the normal nucleotides (NTP’s) found in DNA...
displayed 300 characters
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