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- Investigation of the role of MicroRNA- 223, MicroRNA -381 and MicroRNA- 505 in the regulation of transcription factor NFI-A.

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Issue:

Science

 

Written by:

Dario S

 

Date added:

March 22, 2016

 

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Grade:

B

 

No of pages / words:

8 / 1981

 

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8725 times

 

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Essay content:

It has also been shown to play a role in preconditioning-induced neuroprotective functions (Zheng et al, submitted). Experiments have indicated that human NFIA is negatively controlled by miR-223, in that its translation is repressed by the binding of micro RNA 223 to a binding site on the 3’ UTR of the gene...
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(Fazi et al,2005). MicroRNAs (miRNAs) are endogenously encoded, 22 nucleotide small noncoding RNAs that have been found to direct sequence specific down regulation by mRNA cleavage, cleavage-independent mRNA degradation or translational suppression of mRNA. (Pillai,2005 ; Valencia-Sanchez et al, 2006)...
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