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Essay

Needle found in investigative haystack

Essay specific features

 

Issue:

Science

 

Written by:

Cody S

 

Date added:

July 21, 2014

 

Level:

University

 

Grade:

A

 

No of pages / words:

2 / 322

 

Was viewed:

2548 times

 

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Essay content:

The protein, p53, helps protect against the development of cancer, however reducing it has been shown to extend lifespan in fruit flies by up to 58 percent. Dr Helfand, along with postdoctoral research fellow Johannes Bauer and associates, studied batches of flies modified to have reduced p53 activity in various small areas of their nervous systems...
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In each group, the flies survived their average lifespan of approximately two months. However, when a cluster of fourteen insulin-producing cells in the brains of one group of flies were altered to have lower p53 activity, the flies lived 15 to 20 percent longer than average. No further extension of lifespan was observed when the fruit flies with altered p53 were placed on calorie restricted diets, leading the researchers to believe that p53 reduction within these brain cells is one of calorie restriction's effects...
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