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Neuropeptide Y
Essay specific features


Written by:
Louise H
Date added:
February 28, 2015
Level:
University
Grade:
A
No of pages / words:
8 / 1965
Was viewed:
2075 times
Rating of current essay:
Essay content:
Neuropeptide Y was first reported as a peptide abundant in brain tissue in 1982 [4], and has since been extensively implicated as a pivotal component of neurocircuitry subserving energy balance. During the period since its isolation, emphasis has moved away from clear cut and perhaps oversimplified anatomical divisions of feeding and satiety centres toward a description of the specific neurotransmitters that modulate feeding behaviour and energy expenditure...
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A sixth receptor, Y3 is yet to be cloned, however it has been found to be truncated and inactive in rat and man [5]. The balance of evidence favours the Y1 and Y5 receptors as playing predominant role as they mediate the hyperphagic and obesity-promoting effects of NPY.
The Y1 receptor was the first Y-receptor to be cloned [6]...
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