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PKC-c mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways
Essay specific features
Written by:
Daniel C
Date added:
June 22, 2016
Level:
College
Grade:
A
No of pages / words:
1 / 180
Was viewed:
10258 times
Rating of current essay:
Essay content:
The underlying mission for identifying PKC-cKR as an inhibitor of PKC-c and mTOR activation as well as the proliferation of GBM cells point out that regulation of PKC with PKC-cKR can be useful for the treatment of aggressive brain tumors.
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The introduction of the paper gave sufficient basic information on Glioblastoma multiforme. It was stated that GBM cells have rates of high proliferation within the brain. The astrocyctic tumors express many integrins which promote specific inhibitors and growth factors. When the PKCs are upstream along with other growth factors they aid in the progression of differentiated astrocytic tumors...
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