PKC-c mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways

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Issue:

Science

 

Written by:

Daniel C

 

Date added:

June 22, 2016

 

Level:

College

 

Grade:

A

 

No of pages / words:

1 / 180

 

Was viewed:

10258 times

 

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Essay content:

The underlying mission for identifying PKC-cKR as an inhibitor of PKC-c and mTOR activation as well as the proliferation of GBM cells point out that regulation of PKC with PKC-cKR can be useful for the treatment of aggressive brain tumors.
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The introduction of the paper gave sufficient basic information on Glioblastoma multiforme. It was stated that GBM cells have rates of high proliferation within the brain. The astrocyctic tumors express many integrins which promote specific inhibitors and growth factors. When the PKCs are upstream along with other growth factors they aid in the progression of differentiated astrocytic tumors...
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