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Review of p53 research

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Issue:

Science

 

Written by:

Gloria M

 

Date added:

November 8, 2014

 

Level:

University

 

Grade:

A

 

No of pages / words:

2 / 392

 

Was viewed:

1399 times

 

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Essay content:

Tumor regression or cellular arrest due to the reactivation of p53 in mice with autochthonous tumors can also be foreseen. The importance of autochthonous tumors is that they originate in the organism and mimic real life events. 3. Collected data from this experiment support the conclusion that sustained inactivation of p53 is required for the maintenance of primary, autochthonous lymphomas and sarcomas...
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If p53 is reactivated in a tumor, then tumor regression may occur. 4. Data did support the conclusions and the hypothesis in this paper. • MRI images (Figure 2 d,e) show tumor growth in vivo where p53 was not reactivated. These are the control and did not have Cre Estrogen Receptor. • An increase in tumor volume in both the sarcomas and lymphomas were observed in mice that had inactivated p53...
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