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Rheumatoid Arthritis
Essay specific features


Written by:
Wilma M
Date added:
October 17, 2014
Level:
University
Grade:
B
No of pages / words:
5 / 1347
Was viewed:
3385 times
Rating of current essay:
Essay content:
Included in the analyses were first-degree relatives from 135 simplex and 30 multiplex families. A highly penetrate recessive major gene, with a mutant allele frequency of 0.005, was identified as the most parsimonious genetic risk factor. Significant evidence for heterogeneity in risk for RA was observed for proband gender but not for proband age at onset...
displayed 300 characters
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Significant evidence for heterogeneity in risk for RA was observed for proband gender but not for proband age at onset. Kaplan-Meier risk analysis demonstrated significant evidence for differences in the distribution of risk among first-degree relatives. Although both proband gender and age at onset were identified as important risk factors, proband gender appeared to be the more important determinant of risk, with relatives of male probands having the greatest cumulative risk for RA...
displayed 300 characters
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